- THINKY TOP
- Material cases
- Suspension
Suspension
Suspension to contribute to animal studies
 |
 |
| Phenytoin original bulk （average particle size: about 10μm） |
Pulverized Phenytoin bulk （average particle size: about 100nm） |
 |
 |
| Evaluation by XRD (Powder X-ray diffraction) |
Evaluation by DCS (Differential scanning calorimetry) |
SEM images of phenytoin that is a poor water soluble drug are presented in bulk powder and as processed by the nano pulverizer NP-100. The SEM images reveal that the micro level phenytoin bulk powder has been pulverized into a nano level size. XRD and DSC also indicate that the crystalline nature of phenytoin had been retained after the pulverization and no amorphous had been generated.
＜References＞
Takatsuka, T., Tomoko, E., Yao, J., Kayo, Y and Naofumi., H : Nanosizing Poorly Water Soluble Compounds Using Rotation/Revolution Mixer Chem. Pharm. Bull. 57(10) 1061--1067 (2009)
